It was once thought that kidney gravel occurred regularly in men, however, currently, gear of kidney shingle in women are on the grow. However, since the existence the incidence of the kidney gravel in women is increasing. This has happened because of the illegal lifestyle of nowadays. These years the suitcases of strutuvite kidney gravel in the women are increasing. These appear in number in the women than in the men. They arise due to the continuous bacterial infection of the urinary tract. Among the reasons, the diets, which are affluent only in calories and have, minor proportions of proteins, vitamins, reserves, etc, are the first important trigger for the boost in the kidney shingle in the women. The kidney seed is the disease in which shingle happen in the kidneys. These shingle was the aggregates of the, some unrelated particles and some barren materials from the body and over cells. It is important that the kidney pebbles be detected during the initial stages only. Otherwise, they may be fatal. In most of the cases, the kidney shingle consist of calcium aggregates. The occurrence of the gravel of calcium occurrence is high in most of the women take supplements of calcium and these are the core reasons for the gravel. Another thing that is responsible for the upper occurrence of kidney gravel in women is the consumption of beverages and other alcoholic harvest. The women are more aware to them than then men are. The frequent symptom of the kidney sand includes the grief the worse abdomen during the menstruation. However, this bind is very mild and then most of the period it rest undetected. However, if at the same time they experience some urinary harms as ache during urination, change in incline of urine, blood in urine, or disorders and other symptoms as darkness, fever nausea or sickness and if no other sanity is found for these then this may be the logic. Therefore, ideally, whenever these symptoms happen unexplainably, then this is a thing to unease. Then the reason for them to appear may be homed, then these should be full sincerely. As some sincere disease may have occurred in the body and it may perhaps be kidney rock. If the menstrual bother may persist even after the menstruation or even if it is abnormal, then there maybe incorrect in the inside practice of the body, kindly the kidneys. The kidney pebbles are a solemn diseases, which can grounds complications as infections, blockages, infections, inflammations and eventually they may vanguard to casualty. Therefore, if they are detected they should be impassive from the body as early as doable. On of the treatments regularly worn for the kidney shingle is the uriflow. In this medicine some substances, which have properties through which they can suspend the kidney pebbles, are taken orally. They dissolve the kidney stones and then the stones are impassive from the body through the urine. In addition, the other drugs that are worn in the uriflow dealing also, aid in the removal of the kidney stones from the body and in the relieving the body from throbbing and the other symptoms of the kidney stones. Besides this dissolving, the stones with radiations is also used as another sense for the kidney boulder removal. Another decision is the surgery. The also removes the mineral from body.
Women With Kidney Stones
Diabetes:what You Should Know
This article will explain what you need to know about Diabetes before you or someone you know are unpleasantly surprised.
Diabetes affects around 16 million Americans and about 800,000 new cases are diagnosed each year.
A diagnosis of diabetes is made if your blood glucose reading is 126 mg/dl or higher. People with Type I Diabetes are subject to episodes in which blood glucose levels are very high (hyperglycemia) and very low (hypoglycemia). There are two primary reasons for Diabetes, 1) A prolonged diet high in carbohydrates and 2) Improper and under nourishment. Today, most people with diabetes are only treating the symptoms and not getting to the root of the problem. The prevalence of diabetes has been steadily increasing world over. Diabetes is a disease in which blood glucose levels are above normal.
Insulin is a hormone secreted by the pancreas that is needed to convert sugar and starches into energy needed for daily activity. Type 1 Diabetes is also called Insulin Dependent Diabetes. Insulin is a very important hormone that is needed to convert sugar, starches and other food into energy-the energy we need for daily life. Diabetes is a disease that develops over time, and your health care provider can help you find out whether you are likely to become a diabetic. Diabetes does not care who you are, if testing is painful or if you are tired. Type 2 diabetes is sometimes referred to as mature onset diabetes.
Type II diabetes, in the past, was relegated to the adult population. This form of diabetes is mainly found in children. Smoking is another important risk factor. Among men who smoke, the risk of developing diabetes is doubled. Of the many types of Diabetes, type 1 diabetes, type 2 diabetes, gestational. diabetes and pre-diabetes are the most common. Before the discovery of insulin, type 1 diabetes was fatal. Doing the right things to take care of diabetes can also help to take care of your heart as well. Most Type 2 diabetics don’t have symptoms because the onset. Typically, this type of diabetes will occur during the last three months of the pregnancy , but may potentially occur before that time.
Of the many types of Diabetes, type 1 diabetes, type 2 diabetes, gestational. Diabetes and pre-diabetes are the most common.
Twenty to fifty percent may develop Type 2 diabetes later in life. Children of mothers with gestational diabetes are more at risk for obesity and developing diabetes as teens or adults. It is quite possible to live and eat quite nicely with diabetes if you stick to your plan. The most important thing about dieting with diabetes is that you never lose sight of how crucial it is to do so. Through losing weight, getting the right amount of exercise and controlling your diet, you can manage. Juvenile Onset diabetes is another major form of diabetes that affects many children. The challenge with pre-diabetes is the fact that the condition doesn’t like to reveal itself with noticeable symptoms.
The experience teaches that a mere elimination of symptoms is short-lived, as the underlying causes will soon give birth to new symptoms. Diagnosed with type 2 Diabetes. One of the main causes is overweight. There are a number of causes which give rise to diabetes.
Recently more children are being diagnosed with Type 2 Diabetes. The aim with the treatment of both types of Diabetes is to have blood glucose levels, blood pressure and cholesterol levels as near to average as is possible.
You can prevent or at the very least delay onset of type II diabetes with proper nutrition and exercise.
The thought of getting a disease such as diabetes can be worrisome, it helps to be aware of what diabetes symptoms are and be able to recognize them early enough to get the help you will need to get the disease under control.
For people who are heavily dependent on medicines, exercise cannot replace drugs but it does contribute to normalizing the glucose metabolism.
There have been reports of women diabetics who experienced a decline in sexual activities due to the lack of sensation.
And most diabetics develop heart disease. Research has repeatedly shown that regular physical activity helps reduce the likelihood of having a heart attack or a stroke, aids in weight loss, and improves mood.
It is a very serious disorder, sometimes fatal and is the leading cause of death in Western society because of its damage to the cardiovascular system.
With exercise, weight loss and a healthy diet, pre-diabetic people can and have managed to bring down their glucose levels and have escaped the threat of an insulin-dependent life.
The cause of diabetes is somewhat a mystery, although both family history and environmental factors such as obesity and lack of exercise appear to play roles.
Ketoacidosis is most often seen in Type I diabetics, individuals whose pancreas does not produce enough insulin to allow their cells to take in glucose for metabolism (also the most common form of childhood diabetes).
It should come as no surprise that one of the major causes for the increase in diabetes is due to the obesity problem.
If proper treatment and medication is not administered, at times aggressively, it can lead to fatal complications .
In our days diabetes becomes a big problem even when patients are given insulin and stay on strict diets.
Doctors have always asked themselves why some people develop diabetes and some not, and so, by studying, they have discovered that there are some factors that interfere with the installation of diabetes.
As many studies have shown that an increase in UCP2 function has an important role in pathogenesis of diabetes, this genipin with its inhibitor action on UCP2, represents a solution for improving beta cell function in type 2 diabetes.
A Brief Introduction to Dog Liver Disease
The canine liver is a vitally important organ, one which is involved in practically all biochemical processes and physiological pathways. As a result, when one of the many possible forms of dog liver disease arises, the consequences can be numerous and severe.Anatomy of the Liver
Located in the forward part of the abdomen near the diaphragm, the liver is the largest organ in the canine body and consists of six lobes divided into three regions. This organ receives nutrients through the portal vein and through the hepatic artery. Approximately one third of the blood flowing into the liver travels through the hepatic artery while approximately two thirds travels through the portal vein. While the nutrients that travel through the portal vein originate in the digestive tract, the blood entering the liver by the hepatic artery comes from the heart.Physiology of the Liver
As already alluded to, this complex organ plays a role in nearly all of the body’s biochemical processes. However, some of the most significant functions of the liver include the metabolism of proteins, carbohydrates, and lipids. Another major function of this organ is that it serves as a detoxification system, breaking down and removing toxic substances from the dog’s body. An interesting characteristic of the liver is its amazing reserve capability, requiring only a small portion of liver cells to work at one time. However, the downside of this characteristic is that liver disease may not be detectable until it reaches an advanced stage. At the same time, liver cells do have the ability to regenerate, allowing for full recovery from dog liver disease in some cases.Causes
There are numerous different potential causes of dog liver disease, including traumatic events and medical conditions. Examples of trauma that can give rise to liver disease include being hit by a car, heatstroke, or the ingestion of toxins such as pesticides and certain pharmaceuticals. Other potential causes of canine liver disease include various infections and anatomical or physiological defects of the liver that are present at birth. When it comes to other medical conditions that can give rise to dog liver disease, the possibilities are quite numerous. For instance, anemia and heartworms can lead to damaged liver cells, as can heart disease, cancer, and pancreatitis.Symptoms
Due to the incredible reserve capability of the canine liver, disease of this organ may not become apparent until the problem has advanced quite significantly. Moreover, symptoms and warning signs of dog liver disease tend to be quite subtle and variable in the beginning. However, as the problem progresses, symptoms will become more and more apparent. One of the most classic symptoms of dog liver disease is jaundice, which involves the yellowing of the dog’s skin, gums, and the whites of its eyes. Other classic warning signs include loss of appetite, weight loss, excessive thirst (polydipsia), and increased frequency of urination (polyuria). Lethargy, depression, and a swollen belly are also typical symptoms of canine liver disease. In some cases, diarrhea and vomiting will also occur. In advanced stages of the disease, the afflicted canine may experience confusion, weakness, and even convulsions. Diagnosis
Since the liver is involved in the functions and biochemical processes of so many other organs, the symptoms of dog liver disease are often indistinguishable from those of other diseases. In addition, problems with the liver could actually be a secondary effect of a disease originating in another part of the body. As a result, thorough procedures are necessary in order to reach a firm and confident diagnosis of dog liver disease and to identify its cause. Typically, diagnostic processes that will be carried out in a case of suspected liver disease include a physical examination and blood tests. In addition, x-rays and ultrasound may also be used in order to allow the veterinarian to examine the liver for physical abnormalities. In some circumstances, exploratory surgery and a biopsy may be necessary as well.Traditional Treatment
When a dog is suffering from canine liver disease, the necessary treatment will depend upon the cause of the disease. For example, when a bacterial infection has given rise to the disease, antibiotics will likely need to be administered. When an underlying medical problem such as anemia or cancer is at the root of the liver disease, the underlying condition will need to be dealt with. As a result, required treatment methods can vary quite significantly between cases of dog liver disease.Holistic and Natural Treatment
In addition to the traditional treatment methods required in a particular case of canine liver disease, certain holistic health management strategies can also be very helpful with regards to treatment. Dietary adjustments and natural supplements can optimize nutrition while reducing the stress placed upon the liver. Providing certain nutrients through specific foods, natural supplements, or homoeopathic remedies can also help protect the liver and promote its health. For example, Vitamin E stimulates the production of new liver cells and prevents the build up of toxins. Therefore, in appropriate cases, natural supplements and other holistic health strategies can provide a very beneficial contribution to the treatment process for a dog suffering from canine liver disease.
Kidney Stone Treatment: Why Your Nurse May Suggest a Phosphoric Acid Kidney Stone Remedy
You have kidney stones and you have a decision to make about a kidney stone treatment. After seeing your doctor, the only advice you received was to drink plenty of water for the next couple weeks. Hopefully your kidney stones will pass.
However, as you exit the doctor’s office, you notice a nurse signaling you to come closer. The nurse whispers the best advice you may hear all year. “You can actually dissolve and pass your kidney stones painlessly with a phosphoric acid kidney stone remedy. Just Google it.”
Though a little skeptical, you Google ‘phosphoric acid kidney stone remedy’ and you realize that your nurse could be telling you the truth.
But why didn’t your doctor mention this remedy?
Why You Should Try a Natural Remedy?
Fact! Millions of people try natural remedies each year and kidney stones are one of the simplest ailments to treat naturally.
Fact! Because most kidney stones are made up of calcium, about 90% of kidney stones can be dissolved and passed within 24 hours of remedy.
And though kidney stones are surprisingly easy to dissolve, most hospitals refuse to allow doctors to mention natural remedies. In fact, the most your doctor may be able to suggest is drinking plenty of water.
However, each year many of our customers write e-mails telling us that a nurse recommended a natural remedy. If you are tired of the pain and sick of drinking water like a camel, it is time you learn how you can naturally treat and prevent kidney stones.
Using Phosphoric Acid to Dissolve Kidney Stones
Soft drinks are commonly mistaken as the cause of kidney stones. However, most researchers agree that kidney stones are actually the result of dehydration. Because the body needs water to flush impurities, toxins and calcium, kidney stones are the result of improper hydration.
But why do soft drinks or colas get the bad rap? Because most people who suffer from dehydration drink 2 colas a day and are consistently under hydrated (with water).
Soft drinks trick us into thinking we are not thirsty. In fact, you may go the whole day without thinking you are thirsty because of a compound in colas that fool the brain. But the result could be devastating… kidney stones.
Though soft drinks have a bad reputation when it comes to kidney stones, many researchers are finding that soft drinks are not bad at all. During the 3 year study on ex-kidney stone patients, half of the kidney stone sufferers promised to abstain from any form of carbonated beverage (soft drinks) and the other half tested would continue to drink at least 5 ounces of their preferred soft drink of choice. After the 36 month trial, drinkers of soft drinks were one-third less likely to experience a recurrence of kidney stones. And the men who completely stopped drinking soft drinks were one-third more likely to relapse with kidney stones. What?
The researchers thought just the opposite and were puzzled. Could something be naturally dissolving kidney stones in soft drinks?
Is phosphoric acid a natural dissolvent of calcium?
But What About a Kidney Stone Remedy?
This research study led doctors and scientists to believe that kidney stones can be dissolved naturally. And many experts now believe that the answer for kidney stones is phosphoric acid. To learn about a 100% guaranteed kidney stone treatment that works in less than 24 hours, please visit this Kidney Stone Treatment website.
Become part of the thousands who are naturally passing their kidney stones with a simple 2 ingredient remedy that is baffling medical doctors and costing the pharmaceutical companies millions. You are clicks away from the cure!
Kidney Stone Treatment
Title – Alternative Medicine for the Treatment of Diabetes
Bhupesh Chandra Semwal 1* Sonia Singh1, Dr. Kalyani Divakar2
Introduction-Diabetes mellitus often referred to simply as diabetes. Diabetes is a syndrome characterized by disordered metabolism and abnormally high blood sugar, hyperglycemia resulting from insufficient levels of the hormone insulin. The world health organization recognizes three main forms of diabetes mellitus type1 type2 and gestational diabetes. Gestational diabetes occurring during pregnancy. Which have different causes and population distributions. While, ultimately, all forms are due to the beta cells of the pancreas being unable to produce sufficient insulin to prevent hyperglycemia, the causes are different. All types have been treatable since insulin became medically available in 1921. Type 1 diabetes, in which insulin is not secreted by the pancreas, is directly treatable only with injected insulin, although dietary and other lifestyle adjustments are part of management. Type 2 may be managed with a combination of dietary treatment, tablets and injections and, frequently, insulin supplementation. While insulin was originally produced from natural sources such as porcine pancreas, most insulin used today is produced through genetic engineering, either as a direct copy of human insulin, or human insulin with modified molecules that provide different onset and duration of action. Insulin can also be delivered continuously by a specialized pump which subcutaneously provides insulin through a changeable catheter1.
Classification of diabetes-Type one diabetes mellitus Type two diabetes mellitus Gestational diabetes mellitus2Signs and symptoms-
Frequent urination, Excessive thirst, Extreme hunger, unusual weight loss, Increased fatigue, Irritability, Blurry vision 3
Top Risk Factors for Type 2 Diabetes
Obesity
An excessively high body weight increases diabetes risk. The Body Mass Index ( BMI) is a simple, widely accepted means of assessing body weight in relation to health for most people aged 20 to 65 (Exceptions include people who are very muscular, athletes, pregnant or nursing.) A BMI greater than 27 indicates a risk for developing type 2 diabetes and other health problems which include cardiovascular disease, and premature death.
Apple-shaped figure
Individuals who carry most of their weight in the trunk of their bodies (i.e., above the hips) tend to have a higher risk of diabetes than those of similar weight with a pear-shaped body (excess fat carried mainly in the hips and thighs). A waist measurement of more than 100 cm (39.5 inches) in men and 95 cm (37.5 inches) in women suggests an increased risk.
Sedentary lifestyle
Being overweight – another risk factor for Type 2 – can be prevented by regular physical activity. A second, independent benefit of regular physical activity is improved blood sugar control in persons who already have type 2 diabetes.
Unhealthy Eating Habits
Ninety% of people who have been diagnosed with type 2 diabetes are overweight. Unhealthy eating contributes largely to obesity. Too much fat, not enough fiber, and too many simple carbohydrates all contribute to a diagnosis of diabetes. Eating right is can turn the diagnosis around and reverse or prevent Type 2.
Increased Age
It’s a sad but true fact. Age increases the risk of type 2 diabetes. The older we get, the greater our risk of type 2 diabetes. Even if an elderly person is thin, they still may be predisposed to getting diabetes. Scientists theorize that the pancreas ages right along with us, and doesn’t pump insulin as efficiently as it did when we were younger. Also, as our cells age, they become more resistant to insulin as well.
High Blood Pressure and High Cholesterol
High BP and high cholesterol are the hallmark risk factors for many diseases and conditions, including type 2 diabetes. More than 40 percent of people with diabetes have abnormal levels of cholesterol and similar fatty substances that circulate in the blood. These abnormalities appear to be associated with an increased risk of cardiovascular disease among persons with diabetes.
Family History and Genetics
It appears that people who have family members who have been diagnosed with type 2 diabetes are at a greater risk for developing it themselves. African Americans, Hispanic-Americans and Native Americans all have a higher than normal rate of type 2 diabetes.
History of Diabetes in Pregnancy
Nearly 40 percent of the women who have diabetes during their pregnancy go on to develop type 2 diabetes later, usually within five to ten years of giving birth. Giving birth to a baby that weighs more than nine pounds (4 kg) is another symptom of gestational diabetes.
Impaired Glucose Tolerance
Impaired glucose tolerance or impaired fasting glucose can precede the development of type 2 diabetes. These conditions are determined through blood tests. While persons affected with these problems do not meet the diagnostic criteria for diabetes, their blood sugar control and reaction to sugar loads are considered to be abnormal. This places them at higher risk, not just for the development of type 2 diabetes (an estimated one in ten progress to type 2 diabetes within five years), but also for cardiovascular disease. For this group, preventive strategies including lifestyle changes and regular screening for diabetes mellitus must be a priority4.
Alternative medicine for treatment of diabetes-
Ginseng -Although there are several different types of ginseng, most of the promising studies on ginseng and diabetes have used North American ginseng (Panax quinquefolius). Those studies have shown that North American ginseng may improve blood sugar control and glycosylated hemoglobin (a form of hemoglobin in the blood used to monitor blood glucose levels over time) levels.
Chromium- Chromium is an essential trace mineral that plays an important role in carbohydrate and fat metabolism and helps body cells properly respond to insulin.
Magnesium- Magnesium is a mineral found naturally in foods such as green leafy vegetables, nuts, seeds, and whole grains and in nutritional supplements.Magnesium is needed for more than 300 biochemical reactions. It helps regulate blood sugar levels and is needed for normal muscle and nerve function, heart rhythm, immune function, blood pressure, and for bone health. Some studies suggest that low magnesium levels may worsen blood glucose control in type 2 diabetes. There is also some evidence that magnesium supplementation may help with insulin resistance.
Cinnamon-Cinnamon is a glycosides it improves blood glucose control in people with type 2 diabetes.
Zinc- The mineral zinc plays an important role in the production and storage of insulin. There is some research showing that people with type 2 diabetes have suboptimal zinc status due to decreased absorption and increased excretion of zinc. Food sources of zinc include fresh oysters, ginger root, lamb, pecans, split peas, egg yolk, rye, beef liver, lima beans, almonds, walnuts, sardines, chicken, and buckwheat.
Aloe Vera Gel-Although aloe vera gel is better known as a home remedy for minor burns and other skin conditions, recent animal studies suggest that aloe vera gel may help people with diabetes. A Japanese study evaluated the effect of aloe vera gel on blood sugar. Researchers isolated a number of active phytosterol compounds from the gel that were found to reduce blood glucose and glycosylated hemoglobin levels.
Gymnema- Several preliminary studies suggest that the herb gymnema can lower blood sugar levels in people with type 2 diabetes. Because gymnema may lower blood sugar levels, people taking medications for diabetes or using insulin shouldn’t take gymnema unless they are closely monitored by their health care provider
Vanadium-Vanadium is a trace mineral found naturally in soil and many foods. It is also produced during the burning of petroleum. Vanadium has been found to improve insulin sensitivity and reduce blood sugar in people with type 2 diabetes. It appears to mimic many of the actions of insulin in the body. The use of vanadium for diabetes, particularly without the supervision of a qualified health care practitioner, is not recommended, because the dose needed to affect blood glucose levels can be potentially toxic. The typical amount of vanadium found in the average diet (less than 30 micrograms per day) appears to have little toxicity5.
Neem- The leaves of Neem posses’ anti-diabetic properties. The juices of these leaves are helpful in controlling the blood sugar level in diabetics. Neem is in fact an herbal medicine used for the treatment of various other diseases also such as skin problems, warm infections, ulcer etc.
Sweet potato leaves- The leaves of sweet potato are high value in preventing diabetes, by lowering blood sugar level. It is highly nutritious vegetable. Preparation of sweet potato leaves is used in the tea of diabetic patients.
Madhuca- The Indian name for Madhuca is Madhua it is also posses’ excellent anti-diabetic properties and it is highly beneficial in treating raised blood sugar levels.
Mango leaves- The leaves of Mango helps in lowering the blood sugar levels in diabetics. The fresh leaves of mango are socked in water for an overnight. Then they are squeezed well in the water before filtering them in the morning6.
Discussion and Conclusion- Managements of diabetes with the agents devoid of any side effects is still challenge for the medical system. This has lead to increase in the demand for natural products with antihyperglycemic activity having fewer side effects. Metabolic imbalance causing diabetes mellitus is a characteristic of materialistic world. Differences in social structure, psychic stress, obesity, hormonal imbalance and heredity are optimizing the growth of pandemic. Increasing population with diabetes has a huge requirement of effective remediation. The vast variety of medicinal plants, which are used traditionally for their anti-diabetic property. However, careful assessment including sustainability of such herbs, ecological and seasonal variation in activity of phyto-constituents, metal contents of crude herbal anti-diabetic drugs, thorough toxicity study and cost effectiveness is required for their popularity. These efforts may provide treatment for all and justify the role of novel traditional medicinal plants having anti-diabetic potentials.
References
http://www.diabetesmellitus-information.com/diabetes_herbs.htm
http://www.umm.edu/ency/article/002072.htm
http://www.diabetes.org/diabetes-symptoms.jsp
http://www.phac-aspc.gc.ca/ccdpc-cpcmc/diabetes-diabete/english/risk/index.html
http://altmedicine.about.com/cs/conditionsatod/a/Diabetes.htm
http://www.diabetesmellitus-information.com/diabetes_treatment.htm
Increasing Evidence Suggests Liver Support May be Effective in Compromising the Effects of Hepatitis-engendered Cirrhosis
The Hepatitis-Cirrhosis Connection
According to the American Liver Foundation, more than 25 million Americans are afflicted with liver and gallbladder disease and more than 43,000 die of liver disease each year. While several factors contribute to liver damage, viral hepatitis is the single most important cause of liver disease in the United States and worldwide. Roughly 200 million people worldwide are infected with the Hepatitis C virus (HCV). 4.9 million of those are in the United States (estimates go as high as 15 million) and 5 million in Western Europe. For every one person infected with the AIDS virus, there are more than four infected with Hepatitis C. There are up to 230,000 new hepatitis C infections in the U.S. every year. Currently, 8,000 to 10,000 deaths each year are a result of HCV. Within the next 10-20 years, chronic hepatitis C is predicted to become a major burden on the health care system as patients with no symptoms progress to end-stage liver disease and develop hepatocellular carcinoma. Predictions in the USA suggest that there will be a 60% increase in the incidence of cirrhosis, a 68% increase in hepatoma incidence, a 528% increase in the need for transplantation, and a 223% increase in liver death rate.
The roles of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in causing hepatocellular carcinoma (HCC) are well documented. The frequency of HCC correlates with chronic HBV infection rates. HCC is a cancer arising from the liver. It is also known as primary liver cancer or hepatoma. HCC is the fifth most common cancer in the world and the majority of patients with HCC will die within one year because of the cancer. The majority of primary liver cancers (over 90 to 95 %) arises from liver cells and is called hepatocellular cancer or carcinoma. In 1990, the World Health Organization estimated that there were about 430,000 new cases of HCC worldwide, and a similar number of patients died resulting from this disease. Moreover, recent data show that the frequency of HCC in the U.S. overall is rising. Is there a way to curb this rise?A Healthy Liver is Essential!
While there is no cure for hepatitis and no completely effective treatment, the threats resulting from HCC, cirrhosis, and various hepatitis strands may best be combated by supporting the liver with natural supplements. Extreme Health’s Liver Support Formula
This extremely effective combination of ingredients has Double Blind Studies verifying decreases in degenerative liver damage in patients with chronic liver disease (cirrhosis of the liver) in as few as 30 to 90 days. This combination has proven studies for detoxifying the liver, normalizing liver metabolism and preventing further liver damage due to internal and external toxins like alcohol, cigarettes, long term pharmaceutical use, and environmental poisons
The artichoke bud / sarsaparilla extract utilized in Extreme Health’s Liver Support Formula is an entirely unique complex of phytochemicals extracted from the bud of a hybrid artichoke plant (Cynara floridanum) and the root of the sarsaparilla plant (Smilax officinalis) which can be found at www.extremehealthusa.com or by calling 1-800-800-1285. Proprietary extraction process uses a method in which all plant materials are first combined, macerated, and put into a distilled water / ethanol solvent. This allows the plant materials to interact within the solvent resulting in an exceptional, health-providing formulation of polyphenols and flavonoids.
The artichoke has a long folk history in treating many liver diseases. Recent evidence supports this longtime use. The active ingredient in artichoke is cynarin. This compound is found in highest concentrations in the leaves. Cynara extract has demonstrated liver-protecting and regenerating effects, and promotes the outflow of bile from the liver to the gallbladder. This is very important because if the bile is not being transported adequately to the gallbladder, the liver has an increased risk of being damaged.
Again, there is no cure or completely effective treatment for hepatitis, however the risk of hepatitis-related cirrhosis should not be ignored. Extreme Health is proud to offer perhaps the only liver support protocol with Double Blind Studies verifying its ability to decrease cirrhosis-related liver damage.The Liver’s Functions Include
An expanding corpus of scientific studies verifies the healthy liver’s prophylactic role in maintaining optimal health. This is precisely due to the liver’s role in regulation, synthesis, and secretion of substances key to maintaining a healthy body. The liver’s functions include, but are not limited to the following:
1) Converts nutrients into energy
2) Helps resist infection
3) Metabolizes proteins
4) Helps regulate blood-sugar levels
5) Filtering and removing toxins ts
6) Removing drugs in our system 12) Manufacturing new body proteins
7) Manufacturing and storage of bile
Removing bacteria from our system
9) Regulating fat storage
10) Manufacturing protein and nutrients
11) Storing iron and essential nutrien
We easily comprehend why the liver is considered the body’s refinery. Accordingly, an overburdened, toxic, or otherwise diseased liver necessarily comprises centrifugal detoxification organs such as the kidneys and gallbladder and can result in extreme pain and even death within 12 to 24 hours! Reciprocally, various diseases and viruses actually engender liver damage; the most dangerous of which is potentially hepatitis.Complications
- 25,000 Americans die of cirrhosis, the seventh leading cause of death in the U.S.
- 85% of individuals infected with HCV will develop long-term infection.
- 75% of individuals may develop chronic liver disease.
- 15% of individuals may develop cirrhosis over a long period of time.Fatty Liver (Steatosis) Steato Hepatitis / Cirrhosis
Fatty liver or steatosis is a common condition where fat has accumulated within liver cells (hepatocytes) without causing any specific symptoms.Recent studies demonstrate that a fatty liver of either alcoholic or non-alcoholic origin can lead to inflammation, cell death, and fibrosis (steatohepatitis), and eventually even cirrhosis.
To receive a complete copy of the double blind studies, please visit ExtremeHealthUSA.Com , or call to order 1-800-800-1285
Know About Kidney Disease Complications
Kidney disease is an extremely broad term and includes dozens of kidney disorders and hundreds if not thousands of diseases having an effect on the kidney. The kind of complications seen in kidney disease depends a lot on what the kidney disease is and how much kidney function remains.Complications of kidney disease are secondary conditions, symptoms, or other disorders that are affected by kidney disease. In several cases the difference between symptoms of kidney disease and complications of kidney disease is still ambiguous.The listing of complications that have been revealed in many sources for kidney disease consist of kidney failure, anemia, Dialysis-related amyloidosis (DRA) – from dialysis treatment, Vitamin D deficiency, Excessive serum phosphorus, Bone thinning, and Osteoporosis.Diabetes is the number one cause of kidney disease. In truth, high blood pressure and diabetes are the leading causes of kidney disease. This is responsible for probably 70 percent of kidney failure cases with diabetes accounting of 44 percent of kidney failure cases. The early stages of kidney disease have virtually so signs . It attacks your body and by the time it is detected, the damage is so problematic that it might well be too far to prevent kidney failure. Once your kidneys fail, you have two options: dialysis or kidney transplant. If you do not receive either of these, you will die.How Diabetes causes Kidney DiseaseWhen both kidneys are serving properly, the glomeruli (tiny filters that are in the kidneys) keep all proteins inside of your body. Protein is necessary for many operations within your body and are vital to keep you healthy. Diabetes causes a high concentration of glucose in the blood which damages the glomeruli. The result is that they can no longer keep the protein in the body and it is leaked into the urine from the kidneys.When kidneys are thus damaged they no longer work correctly and do not clean our waste and extra fluids as they should. When this occurs, the fluids and waste build up in the body instead of being expelled in the urine.To make a diagnosis on PKD, your doctor will acquire an entire medical history and do a careful physical examination. He/she will be able to consider any enlargement of the kidneys if the disease has developed. Your doctor will direct tests that assess your kidney function, in addition to scans of the kidney area to make sure for enlargement and cysts. He/she can operate a kidney biopsy, in which a small sample of kidney tissue is uninvolved for inspection under a microscope.
To Compare the Role of Glibenclamide and Pioglitazone Drugs in Type 11 Non- Insulin Dependent Diabetes Mellitus Patients
To compare the role of glibenclamide and pioglitazone drugs in type 11 non- insulin dependent diabetes mellitus patients.Authors:Raj kumar chohan,Mashori Ghulam Rasool,Bhurgri Ghulam Rasool,Shamim-u-Rehman,DahriGhulam mustafa,Anis-u-rehman.Introduction:-
To compare the role of glibenclamide and pioglitazone drugs in type 11 non- insulin dependent diabetes mellitus patients.
Authors:Raj kumar chohan,Mashori Ghulam Rasool,Bhurgri Ghulam Rasool,Shamim-u-Rehman,DahriGhulam mustafa,Anis-u-rehman.
Introduction:-
Diabetes comes from the greek word for ‘SIPHON” which one is the first term and implies for a lot of urine is made .The trm “mellitus” comes from a laton word, “met” which means “honey” and was used because the urine was sweet (Wheeler,2004)
Diabetic ketaocidosis is one of life threatening condition requiring some data hospitalization and treatment. Recognition of this condition is of almost importance, because even small delays can have an impact on survival (Nattrass, 2006). Hypoglycaemia are involved in insulin induced episodes in individuals with diabetes. Probably the major factor prescribing, insulin treated patient from achieving the glucose targets needed to prevent diabetic complications. The incidence of hypoglycaemia reflects the inadequancy of current mathods of insulin delievery which lead ot inappropriately high insulin concentration, particularly some persons after eating more foods at night onset of blindness and also a major risk factor heart disease and stroke
(Heller, 2003).
TYPES OF DIABETE MELLITUSTYPE 1 DIABETES MELLITUS (IDDM): Type I diabetes affect children of all ages, both sexes and all athenic groups. type 1 diabetes usually occurs by mechanisms. It is most common metabolic condition in children and adolescents (Bui, 2004). Type1diabetes is characterized by immune mediated destruction of pancreatic b -cells resulting in insulin deficiency. This results in a common biochemical end point of hyperglycaemia and risk of ketoacidosis, but the clinical presentaion varies, widely depending on the rate and degree of b -cells failure (Lambert & Bingley. 2005). Type II diabetes mellitus (NIDDM):
TYPES OF DIABETE MELLITUS
TYPE 1 DIABETES MELLITUS (IDDM):
Type II diabetes mellitus (NIDDM):
Type II diabetes is a complex metabolic disorder associated with, b -cells dysfunction and with varying degree of insulin resistance primary pathogenic factors leading insulin resistance leading to type 2 diabetes and decreased insulin, secretion which arise from abnormalities with in liver, skeletal muscle and pancreatic b -cells (charles & clark, 1996).
GESTATIONAL DIABETUS MELLITUS : Women who develop glucose intolerance in late pregnancy and womens who with previously undiagnosed diabetes.
GESTATIONAL DIABETUS MELLITUS
Women who develop glucose intolerance in late pregnancy and womens who with previously undiagnosed diabetes.
SECONDARY DIABETUS MELLITUS:
SECONDARY DIABETUS MELLITUS:
Secondary diabetes is due to disease of the pancreatic and endocrime system, genetic disorders, or exposure to chemical agents.
Type – I diabetes formerly known as insluin dependent diabetes mellitus (IDDM), is characterized by the destruction of the pancreatic beta cells that produces inslulin
Type – I diabetes formerly known as insulin dependent diabetes(IDDM),is characterized by the destruction of pancreatic beta cells that produces insulin.Type-1 diabetes occures most often in children and young adults but it can occures at any age.(Anderson et al 2007).
Type-11 diabetes is not straight uprward. A pancreas that does not produce enough insulin. Liver that release too much glucose,muscle cells that do not readily take in glucose.(Carren 2008)
Many genetic factors are involved in the development of diabetes.Because of new genetic methodology researchers are closers to identifying all of the cadidate gene for both non –insulin dependent and insulin dependent diabetes(Bernhard,1995).
Woman who had gestation diabetes are more likely to develop Type-11diabetes themselves.Pergnant women with diabetes are another disadvantaged group.They need much more intensive antenatal care and close monitoring of blood sugar,blood pressure and weight.(jawed2006)
Over weight children the progression of child obesity into adulthood is associated with early develop of complications, including IgpG2 diabetes and cardiovascular disease.Type diabetes is the most common clinical form of diabetes accountingforabout 90% of all cases,it is currently undergoing world wide epidemic. Type 11diabetes mellitus is caused by body’s infective use of insulin, it is often results from excess body weight and physical inactivity(WHO 2007).
PREVALACES& IINCIDENCE :
PREVALACES& IINCIDENCE
Diabetes mellitus increases with aging, in 200 the prevalance of diabetes,it was estimated to be 0.19% people<20 years old and 8.6% in people>20 years old.There is considered geographic variation in the incidence of both type-1 and type-11 diabetes mellitus.Scavandinvian has the highest incidence of type-1 diabetes mellitus e.g in Finland, the incidence is 35/100,000 per year the pacific rim has a much lower rate in japan and china the incidence is 1 to 3/100,00 per year of type-1 diabetes mellitus, Northern Europe and the United States share an intermediate rate (8to17/100,000 per year).The prevalence of type 11 diabeties mellitus is highest in certain pacific island, intermediate in countries such as India and the United States, and relatively low in Russia and China.This variability is likely due to genetic, beharioral and enviromental factors(Power 2005).Diabettes mellitus prevalance also arises among different ethic population within a given countries it is common inall ethnic groups its prevalance increased with age and more than 5% of individuals of more than 65 years of age have diabetes mellitus (David Owerback 1988).The World wide prevalence of diabetes mellitus has risen dramatically over past two decades.The prevalence of type11 diabettes mellitus is expected, type 11 diabetes mellitus is more prevalent among Hispanies Native Americas,African,American,and Asians, pacific Islanders than in non- Hispanic whites,the incidence is essentially equal in woman and men in all populations. Type 11 diabetes is becoming increasingly common because people are living longer,and the prevalence of diabetes increases with age it is also seen more frequently now than before in young people, in association with the rising prevalenceof childhood obesity although type11 diabetes still countries with the estimated nubers of cases of diabetes in 2000and 2030.
Rank Country
2000 Individuals country with diabetes (milloins)
Country
2030 Individuals with diabtes (Million)
India
31.7
India
79.47
China
20.8
China
42.3
USA
17.7
USA
30.3
Indonesia
8.4
Indonesia
21.3
Japan
6.8
Pakistan
13.9
Pakistan
5.2
Brazil
11.3
Russian federation
4.6
Bangladesh
11.1
Brazil
4.6
Japan
8.9
Italy
4.3
Philippines
7.8
Bangladesh
3.2
Egypt
6.7
(Wareham& FOROUHI 2OO6)
DRUG TREATMENT OF DIABETIES MELLITUS :
DRUG TREATMENT OF DIABETIES MELLITUS
Biguanides lower blood glucose, they increase glucose uptake and utilize in skeletal muscle there by reducing insulin resistance, and reduce hepatic glucose production (gluconeogenesis).Lower blood glucose, addionally reduces low denisity and very low denisity lipoproteins (LDL and VLDL) respectively. Metformin has a half life of about 3 hours and is excreted unchanged in the urine.Clinically metformin used in type 2 diabetic who are obese and who fail treatment with diet alone.Adverse effects are produced dose related gastrointestinal disturbances e.g anorexia,diarrhoea,nausea,lactic acidosis rare but potentially fatal toxic effect.(Dale,2003).
Improving insulin sensitivity by activating certain genes involved in fat synthesis and carbohydrate metabolism Rosigilitazone and Piogiltazone are currently approved.Thiazolidinediones. Thiazolidinediones do not cause hypoglycemia when used alone,although they are usually taken in combination with sulfonylurease.
In some incouraging studies, thaiazolidiniones have produced very favorable effects on the heart, including reducing blood pressure and improving triglycerides and cholestrol levels including increasing HDL level,the good cholestrol. They may also block a molecule called 11 Best HSK that may play a significant role in metabolic syndrome,as well as diabetes type11. One study also sugessted that Rosiglitazone may even improve beta cells functions and so help prevent progression of diabetes.Anemia, weight gain, increased risk of fluid buildup, may worson heart failure.Troglitazone,was withdrawn after a few reports of heart failure.Liver failure abd death.Current Thiazoldinediones don not appear to pose the same effects on the liver although there have been a few reports of liver injury.
In patients with dietry failur the choice of a sulfonylurea agent or insulin therapy has been controversial and empric in favour of insulin therapy are the studies, who reported marked improvement post receptor diagnostic after intensive short term therapy in untreated type 2 diabetes mellitus (Scarlett et al,1984) Sulfonylureas further classified into two groups or generations based on their potency,duration,drug interaction,side effects profiles. Sulfonylureas enhance insulin action in cells in culture and stimulate the synthesis of glucose transporters (Jacobes et al 1998).A sulfonylurea drug should normally be the insulin secretagogue of choice, NICE (National Institute for Clinical Excellence) also recommends that a generic ,drug should be perscribed (Scsade et al1998).
RESEARCH DESIGN AND MATERIAL AND METHODS:
RESEARCH DESIGN AND MATERIAL AND METHODS:
This study was conducted in the deprtment of Pharmacololgy and Therapeutics,Basic Medical Science Institute,Jinnah,Postgraduate Medical Centre,karachi under kind supervision od DRr:GhulamRsool Mashori,Associate Professoer and Head OF Department Of Pharmacology and Therapeutics in colloboration with Medical Outpatient Department Unit111 and Filter Clinic, Medical Department, JPMC,Karachi.
Seventy NIDDM (type-II)diabetic patients were initially enrolled in the study from the filter clinic/ out patient department Medical Unit III ,and diabetic clinic.Out of this 60 diabetic patients were associated in whole period of study, remaining 10 patients were dropped due to poor comlpiance or change in residential place.All the patients were divided in two main groups,groupI and in group II these patients were selected in this study according of inclusion and exclusion criteria.
INCLUSION CRITERIA :
INCLUSION CRITERIA
EXCLUSION CRIRERIA :
EXCLUSION CRIRERIA
MATERIAL:
MATERIAL:
DRUGS
DRUGS
Tab:Daonil 5 mg (Aventis Pharma)
Drug category:Sulphonylurea.
Generic Name: Glibenclamide.
MFGLIC:No.000007 RegistrationNO.000220
MFG Date:0-06
EXP Date:7-10
Lot NO:B230
Tab:piozer (Hilton Pharm) PvtLTd.
Tab:Poizer 15mg
Drug category:Thaiazolinedione.
Generic Name:Pioglitazone Hydrochloride.
MFG LIC: O.000136 Registration No.03270
MFG Date:3-06
EXP Date:3-o9
Lot No:6287
Tab: Poizer (Hilton Pharma)pvt ltd.
PARAMETERS:
Fasting Blood Sugar (FBS).
Random Blood Sugar (RBS).
Weight.
Key words:Diabetes mellitus,Non-insulin diabetes mellitus,Insulin depedent diabetes mellitus, Daonil,poizer,Insulin.
RESULTS:
RESULTS:
Table 1
Table 1
Weight and Blood Sugar level observed on baseline day 0
In group1 and group11
Group 1
Group 11
Pioglitazone n=27
Glibenclamide n=33
Weight
63.37
+ 2.25
¯
62.7
+ 15.56
¯
Fasting Blood Sugar
172.7
+ 13.32
¯
188.42
+ 12.o5
¯
Random Blood Sugar
285.11
+ 15 .532
¯
284.18
+ 17.07
¯
All Values are expressed in Means± SEM.
FIGURE-1 weight and blood sugar levels observed on baseline (day-o)
In table No shpwing the weight (KG’S) and blood sugar (msg/dl0 levels which is observed on baseline (day-0) in both groups 9group: 1 & group11)
Group: 1 Weight in (Kg’s) mean + SEM) IS 63.37±2.25 Fasting blood sugar 172.7±13.32,and Random
blood sugar 285.11±15.32
Group:11 Weight (KG’s0 (mean +SEM)62.7±1.56 Fasting blood sugar (mg/dl0 188.42±12.05, Random blood sugar is 284.18±17.03.
Group:11
Figure 2: showing the weight and blood sugar levels observed in base line (day-0) in group: 1 and group 11 weight in 9kg’s) its mean values are 63.37,62.7, Fasting blood sugar in (mg/dl) is 172.71, 188.42 Random blood sugar (mg/dl) is 285.11 &284.18.
TABLE: 2
Peroidic Observation In All Parameters Group1
Goup1(Pioglitazon) n=27
P-value
Day-0
Day-45
Day-90
Day-0to45
Day-45-90
Weight
63.37
±2.25
63.63
±2.26
63.63
±2.23
>0.05
(NS)
>0.05
(NS)
Fasting blood sugar
172.7
±13.32
165.04
±8.98
153.37
±7.59
>0.05
(NS)
0.05
(NS)
Randomblood sugar
285.11
±15.32
279.78
±13.63
255.56
±12.65
>0.05
(NS)
>0.05
(NS)
All values are expressed in Mean±SEM .(NS) Non significant.
TABLE NO:2
TABLE NO:2
Showing the periodic observations in all parameters in group 1 (piogiltazone) (n+27) weight P.value (day 0 to day 45)>0.05 (NS). Fasting blood sugar >0.05 (NS) Random blood sugar >0.05 (NS) P.values day 90 weight >0.05 (N.S), FBS>0.05 (N.S) 7RBS >0.05(N.S) NON SIGNIFICANT
FIGURE:2 Showing the periodic observation in all parameters in group 1 on day0 day 45& day-90.Mean values in weight (Kg) is 63.37,63.26,63.63, fbs (mg/dl) 172.7,165.04,153.37,RBS(mg/dl) 285.11,279.78,255.56.
TABLE NO3
Peroidic Observation in All Parameters Group11
Group 11 (Glibenclamide)
N=33
P-value
Day-0
Day-45
Day-90
Day-0 to 45
Day-45 to 90
Weight
62.7
±1.56
65.64
±2.10
64.55
±1.92
>0.05(NS)
0.05(NS0
Fasting blood sugar
188.42
±12.05
168.45
±10.99
140.06
±5.68
>0.05(NS)
>0.05(S)
Random blood sugar
284.18
±17.03
220.12
±13.39
170.94
±5.80
<0.005 (MS)
0.002(MS0
(s) significant, (MS) moderate significant
All values are expressed in Mean±SEM.
Table No3:
Table No3:
Showing the periodic observation in all parameter in goup:11, Group:11 containing drug (Glibenclamide),no of patients (n=33).It’s P-value on day 0 to day 45 on weight >0.05(NS),FBS>0.05(N.S) RBS<0.005 (MS) <0.01- AND DAY 45 TO DAY 90 WEIGHT >0.05 (NS) FBS (0.05) RBS <0.002(M.S0 moderately significant.
Figure 3:Shwing the periodic observations in all parameters in Group 11 weight 62.7,65.64,64.55,FBS (MG/DL) 188.42,168.45 140.06,RBS(mg/dl) 284.18 220.12, 170.94 (on day-0-day 45 to 90).
DISCUSSION:
DISCUSSION:
In Denmark Beck-Nielsenet al,skillman TG (1981) published studies demonstation that glyburide increased he number of receptors on the monocytes of patients with type 11 diabetes mellitus. Some patients were treated with diet and in cobination of second generation sulfonyureas agents Wie. The numbers of insulin receptors all patients were measured before and after the treatment.Intrvenous glucose test shows the persistent impairent of insulin secretion afterthe starting of drug therapy.However those patient who were on drug Pioglitazone some results were obtained of insulin secretion in the impairment in early drug drug therapy.Clinical observations have suggested that the second generation sulfonylureas may exert their effects by potentiating insulin released by other primary stimulators Insulin secreting drug.
According to the study of WilliamC Dukworth et al(1972), aftr the chronic treatment with sulfonylureas it is well documented that plasma insulin levels were decreased in response to oral glucose load. This apparently occures even though glucose tolerance is improved over pre-treatment, levels,present study clearly support that study.
The result og group 11 correlates with the research conducted by Bonnie &Kimmel (2005) produces the same results as FBS reduces from baseline, and at the end of study,with an overall 23.44%,reduction,while with the results showed at the end of study peroid p-value were (p<0,001).
Similarly Michael Alvarsson et al (2003) conducted a similar type of study and the found and overall changes of change of 22.11% in Fbs and 40.88% in Rbs at the end of trial p-value were (p<0.001).
However a study conducted by (Stone &Brown in (2003) didnot match to our results in the parameter of FBS and observer a reduction of 26.22%.
CONCLUSION:
CONCLUSION:
In the light of study discussion it is obiovus the glibenclamide was more effective,tolerable and safer than pioglitzone in a short duration.Diabetes Mellitus is chronic prolong disease for whole life.Poor community can afford it easily,on base of marketing of this drug in pakistan diabetes patients easily go and purchase economically,in fact ,mostly people buy it from pharmacy without dr’s perscription,because pharmacist and patient both of know about this disease.Just like dispirin as analgesic,it is famous anti-diabetic drug in our states as compared of other anti-diabetic drugs.
REFERNCES:
REFERNCES:
Liver Cancer
The liver, one of the largest organs of the body, has many important functions that keep a person healthy. It removes harmful material from the blood, produces enzymes and bile that help digest food and converts food into substances needed for life and growth.How can cancer involve the liver?There are two ways in which cancer can involve the liver. The cancer can arise from the liver itself (primary liver cancer) or it can spread to the liver from a primary tumour at another site (secondary, or metastatic, cancer).In the UK, secondary liver cancer is about 28 times more common than primary liver cancer. Each year there are about 70,000 patients in the UK with secondary liver cancer and about 2,500 with primary liver cancer.Liver cancer can arise in two ways:· Primary liver cancer (most commonly hepatocellular carcinoma) originates in the liver. · Metastatic liver cancer results from the spread (metastasis) of cancer from other areas of the body. What is primary liver cancer?Primary liver cancer starts in the cells, bile ducts, blood vessels or connective tissue of the liver. It’s not very common. Primary liver cancer is different from cancer that started somewhere else in the body and spread to the liver (called secondary liver cancer or metastatic liver cancer).The liver is one of the largest organs in the body. It’s found in the upper part of the abdomen on the right-hand side and is protected by the lower ribs. The liver has two parts, called lobes – the right lobe and the smaller left lobe.CausesYour liver is a football-sized organ that sits in the upper right portion of your abdomen, beneath your diaphragm and above your stomach. Your liver processes most of the nutrients absorbed from your small intestine and determines how much sugar (glucose), protein and fat enter your bloodstream. It also manufactures blood-clotting substances and certain proteins. Your liver performs a vital detoxifying function by removing drugs, alcohol and other harmful substances from your bloodstream.What are the main treatments for liver cancer? Surgery for primary liver cancer.Surgery for liver cancer is the best treatment we have if the cancer hasn’t spread. There are two main options· A liver transplant · Surgery to remove the cancer from your liverLiver transplantHepatocellular cancer (HCC) is more likely to develop in people with chronic cirrhosis. Your specialist may suggest a liver transplant if you have cirrhosis of the liver because of previous liver disease, infection with a hepatitis virus or from drinking alcohol. Other TreatmentsYour specialist may suggest one of the following treatments to help control liver cancer· Percutaneous ethanol injection · Radiofrequency ablation · Chemoembolisation · Cryosurgery or cryotherapyNew Treatment Targets Liver CancerIn the interventional radiology suite, physicians use Selective Internal Radiation Therapy to treat patients with inoperable liver cancer.Physicians at the University of Maryland Greenebaum Cancer Center are performing a new treatment for inoperable liver cancer known as Selective Internal Radiation Therapy (SIRT). SIRT is a non-surgical outpatient therapy that uses microscopic radioactive spheres, called SIR-Spheres®, to deliver radiation directly to the site of the liver tumors.
Kidney Stone Causes – Genetic Traits Can Cause Kidney Stones
Kidney Stone FormationOur kidneys function as filters in our body. It has nephrons or fine tube-like filters which excretes the waste from the blood and produces the urine. These nephrons then act as filters of the blood and the wastes collected by pass through the ureter and into the bladder where it becomes urine. In turn, the kidneys expel the urine out of the system. The kidney stones causes are therefore those that detract the kidney from performing these functions.Kidney stones may normally form in the kidneys unnoticed. In fact, they can remain unnoticed if the size of the kidney stone is very small; usually the size can be smaller than a grain of sand. If the kidney expels this size from its system, it will be barely noticeable at all and will not cause any problems or complications.Still, it is best for us to know the kidney stone causes. However, if the kidney stone is stuck in the ureter, this will now have a snowball effect. The kidney stones are in crystal form and can get into contact with calcium and salt sediments that can cause it to enlarge. This will damage the ureter and lead to a high probability of infection.Kidney Stone CausesSeveral circumstances may cause kidney stones but there are still no proven explanations as to why they form. The following are only probable causes: Hereditary reasons – Genetic traits passed on from generation to generation, can cause kidney stone problems. Some are born with high susceptibility to kidney stone formation because they have different ways of absorbing minerals in their body. Others have poor calcium absorption while some have poor metabolism and have difficulty managing certain chemicals.Examples of these chemicals are cystine (a type of amino acid), oxalate (a form of salt), and uric acid. These substances can stick together and crystallize. If they form crystals, then there is a higher possibility of having kidney stone problems.Climate – If a person is lives in a place where there is a very dry climate, he tends to dehydrate easily. Once a person is dehydrated, body will excrete less liquid and thus the urine may come in a more concentrated form. If the urine is concentrated, the minerals and chemicals come in closer contact with each other and may have the opportunity to crystallize and cause damage.Diet – A person’s diet has to change if he is already suffering from kidney stone problems. For example, if you are already suffering from kidney stones caused by uric acid and calcium stones, then, it is best to avoid foods rich in calcium and uric acid.Over the Counter medication – Medications like antacids and diuretic pills may form kidney stones. These medications can contain a lot of calcium and may cause calcium-based kidney stones.Having only one kidney or an abnormally shaped kidney – People who had their kidney removed or donated can have a very high chance of getting kidney stone problems because their kidney will have to take on the function of the missing one and will need to work double time. An abnormally shaped kidney may also mean that the other kidney will have to work double time.Some of the kidney stones causes may promote the occurrence of crystallines in the renal system. Minimizing the risk of forming a stone that will be block the ureter is possible by avoiding dehydration. Keeping one’s urine dilute will not allow the formation of a stone nucleus.
Alvin Hopkinson is a leading health researcher in the area of natural remedies and kidney stone removal. Discover how you can get rid of your kidney stones for good using proven home remedies, all without using harmful medications or drugs. Visit his site now at http://www.nomorekidneystone.com